Dr. rer. nat. Lena Sünke Mortensen

Dr. rer. nat. Lena Sünke Mortensen

MASTER STUDENT

Algorithms for complex data in life sciences

mortensen@izbi.uni-leipzig.de

+49 (0) 341 - 97 16697

Room: 326

ACADEMIC CAREER

  • 2006 BSc in Biology, Westfälische-Wilhelms-Universität Münster
  • 2007 - 2012 International Max Planck Research School in Neurosciences, Georg-August-Universität Göttingen
  • 2012 PhD (Dr. rer. nat.) in the dept. Molecular Biology of Neuronal Signals, Max Planck Institute of Experimental Medicine, Title "Modulation of synaptic transmissioin by the voltage gated potassium channel Eag1"
  • 2013 visiting postdoctoral scientist in Joshua Singer's group at the University of Maryland, USA (5 months)
  • 2012 - 2018 Postdoctoral Researcher in the dept Molecular Neurobiology, Max Planck Institute of Experimental Medicine, Topic: Molecular mechanisms of vesicle release in the mammalian retina
  • since 2018 MSc in Bioinformatics, Leipzig University
  • since 2020 IZBI, Leipzig University

SCIENTIFIC INTERESTS

  • Data mining and integration of high throughput OMICs data
  • Epidemiology of health and disease
  • Neurophysiology

PUBLICATIONS

MISCELLANEOUS

Publications outside of IZBI-work:
  • Mortensen LS, Park SJH, Ke, JB, Cooper BH, Zhang L, Imig, C, Löwel, S, Reim K, Brose N, Demb J, Rhee JS, Singer JH. Complexin 3 increases the fidelity of signalling in a retinal circuit by regulating exocytosis at ribbon synapses. Cell Reports 2016, DOI: http://dx.doi.org/10.1016/j.celrep.2016.05.012
  • Mortensen LS, Schmidt H, Farsi Z, Barrantes-Freer A, Ufartes R, Eilers J, Sakaba T, Stühmer W, Pardo LA. KV10.1 opposes activity-dependent increase in Ca2+-influx into the presynaptic terminal of the parallel fibre – Purkinje cell synapse. J Physiol 2015; 593(1); 181-196
  • Barrantes-Freer A, Kim E, Bielanska J, Giese A, Mortensen LS, Stühmer W, Pardo LA. Functional properties of the plasma membrane of human glioma initiating cells. J Neuropathol Exp Neurol 2013; 72(4):307-3024
  • Ufartes Mas R, Schneider T, Mortensen LS, de Juan Romero C, Heintrich K, Knötgen H, Beilinson V, Möbius W, Tarabykin V, Alves, F, Pardo LA, Rawlins N, Stühmer W. Kv10.1 (Eag1) reactivity to antipsychotic/antidepressant drugs. Hum Mol Genet 2013; 22(11):2247-2262
  • Baune BT, Hohoff C, Mortensen LS, Deckert J, Arolt V, Domschke K. Serotonin transporter polymorphism (5-HTTLPR) association with melancholic depression: a female specific effect? Depress Anxiety 2008;25(11):920-5
  • Domschke K, Hohoff C, Mortensen LS, Roehrs T, Deckert J, Arolt V, Baune BT. Monoamine oxidase A variant influences antidepressant treatment response in female patients with Major Depression. Prog Neuropsychopharmacol Biol Psychiatry 2008 Jan 1;32(1):224-8
  • Kersting A, Kroker K, Horstmann J, Baune BT, Hohoff C, Mortensen LS, Neumann LC, Arolt V, Domschke K. Association of MAO-A variant with complicated grief in major depression. Neuropsychobiology 2007; 56(4):191-6