ACCELERATION OF THE TRANSLATION OF VIRTUAL TWINS TOWARDS A PERSONALIZED MANAGEMENT OF FATTY LIVER PATIENTS
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PROJECT DESCRITION
The ARTEMIs project consolidates mechanistic and machine learning models to create “virtual twins” embedded in a clinical decision support system (CDSS). This supports physicians in the personalized management of metabolic fatty liver disease (NAFLD), which occurs in about 25% of the population. NAFLD ranges from silent disease progression to hepatitis, fibrosis, cirrhosis and hepatocellular carcinoma (HCC), with cardiovascular complications often being fatal.
ARTEMIs predicts disease progression and supports the active monitoring of patients at risk. It shows the effects of new therapies or lifestyle changes and serves as an educational tool for patients. In the case of advanced diseases, it offers support for therapies such as hepatectomy or liver transplantation. It also predicts heart-related risks based on hemodynamic models. A feasibility study is evaluating the benefits of virtual twins and the CDSS in clinical use.
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Project Leader Dr. Höhme, IZBI
Scientific Assistant Deng Zhipeng, Marlene Mertens, Sabrina Schmidt, Qasim Siddiqui
Duration 01.01.2024 – 31.12.2027
Extern Project Website https://www.hoehme.com/
Funding third-party funding EU