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Leipzig offers an excellent research environment for Systems Biology with
the University of Leipzig and in particular with the Faculties
- of Biology, Pharmacology and Psychology (BIO),
- of Mathematics and Computer Science (MCS),
- of Physics and Earth Science (PHYS),
- of Chemistry and Mineralogy (CHEM), and
- of Medicine (MED),
- the Interdisciplinary Centre for Bioinformatics (IZBI)
- the Max Planck Institute for Mathematics in the Sciences (MIS) and
- the Fraunhofer Institute for Cell Therapy and Immunology (IZI).
Leipzig has made very good experience with interdisciplinary research and education. The IZBI has been proved as nucleous for joint projects also in the context of systems biology, bringing together experimentalists and theoreticians from different disciplines. The centre developed strong competence in the field of gene expression data analysis and management, the modelling of tissue formation, analysis and 3D reconstruction of microscopic images, and of genetic evolution. Proteomics competence is integrated into the SyBiL consortium by the DFG Research Centre (SFB 610): "Variation in Protein Conformation: Cell-biological and Pathological Relevance".
Leipzig has successfully evolved as a centre of "red" biotechnology and medical research. The Biotechnological-Biomedical Centre of the University (BBZ) congregates professorships and Junior Research Groups with strong background in biotechnology.
The Interdisciplinary Centre for Clinical Research (IZKF) focuses on disease-related issues with different nexuses with the planned centre. Close cooperation is envisaged with the Core Unit DNA-techniques and micro-array technologies of the IZKF which tightly cooperates with the IZBI.
The Coordination Centre for Clinical Research Leipzig (KKSL) realises the link from drug research to the "patient" via clinical trials with tight relations to disease modelling, drug research, and studies on the molecular origin of diseases. Leipzig has become a major centre for clinical trial research in Germany. In this context, the IZBI, IMISE, and KKSL have established a data management strategy encompassing phenotypic, genetic and high-throughput gene expression and genome-wide cytogenetic scans in a comprehensive way, linking trial management and data warehouse technologies. The technique also permits to provide Web-based data analysis pipelines. Hence, we are prepared to offer a comprehensive database service to the research unit. Likewise the IZBI has established a group experienced in tissue image analysis and morphometry.